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1.
Hamdard Medicus. 2009; 52 (4): 22-27
in English | IMEMR | ID: emr-109807

ABSTRACT

Leaf extracts of Lawsonia inermis Linn. [Lythraceae] were screened for their antimicrobial activity against 11 human pathogenic bacteria [Bacillus subtilis, B. cereus, B. megaterium, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Sal. paratyphi, Shigella dysenteriae, Sh. sonnei, and Vibrio cholerae] and 6 fungal phytopathogens [Alternaria alternata, Botryodiplodia theobromae, Colletotrichum corchori, Curvularia lunata, Fusarium equiseti and Macrophomina phaseolina]. During preliminary screening, the chloroform soluble fraction of L. inermis was found active against all the bacterial test organisms. The antifungal activities of extracts were found non-potential. VLC analysis of chloroform fraction showed 10 groups [A to J] depending on TLC behavior [Rf. value]. Fraction C showed highest antibacterial activity [20-41 mm] against all the pathogens tested at a concentration of 1000 microg/disc. GC/MS analysis of fraction C characterizes 14 components representing 89.14% of the total fraction. The major components were Diisooctylphthalate, 3-Octadecane [E], Heptadecane, 2, 6-Dimethyl etc


Subject(s)
Anti-Infective Agents , Plant Extracts , Phytotherapy
2.
Hamdard Medicus. 2008; 51 (3): 163-170
in English | IMEMR | ID: emr-102222

ABSTRACT

Chakma is the largest tribal community in the Ghagra union of Rangamati District. Majority of them still depend on medicinal plants for the treatment of different ailments. A study was carried out in that area to document their knowledge about medicinal plants. 52 species under 38 families have been recorded which are used for the treatment of 43 diseases. Botanical name, tribal name, parts used and doses are mentioned


Subject(s)
Knowledge , Phytotherapy , Herbal Medicine , Ethnobotany
3.
Hamdard Medicus. 2007; 50 (3): 23-28
in English | IMEMR | ID: emr-128212

ABSTRACT

1,2-Benzenedicarboxylic acid, diisooctyl ester [diisooctyl phthalate] isolated from the roots of Plumbago zeylanica was screened for its antibacterial activity against eleven human pathogenic bacteria viz., Bacillus subtilis, B. cereus, B. megaterium. Escherichia coli, INABA ET [Vibrio], Shigella dysenteriae, S. sonnei, Salmonella typhi, S. paratyphi, Staphylococcus aureus and Pseudomonas mutabilis. The antibacterial activity of the compound was evaluated using the disc diffusion and macrodilution method. The compound showed moderate to good antibacterial activity against almost all the test bacterial pathogens. The largest zone of inhibition 22 mm, 14 mm, 11 mm, and 6 mm in diameter were recorded against Pseudomonas mutabilis at the concentration of 50 micro g, 20 micro g, 10 micro g and 5 micro g/disc respectively. The compound exhibited the lowest MIC [40 micro g/ml] against Bacillus subtilis, B. cereus, B. megaterium, Escherichia coli, Shigella sonnei, Salmonella paratyphi and Pseudomonas mutabilis and MBC [160 micro g/ml] against Bacillus cereus, B. megaterium, Escherichia coli and Pseudomonas mutabilis

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